Allergic contact fingertip dermatitis secondary to proxymetacaine in an ophthalmologist

Fingertip eczema to pooja flowers: Allergic contact dermatitis to Tabernaemontana divaricata and Tecoma stans.

Sir, A 46‐year‐old woman presented with hyperkeratotic eczema and painful fissuring of the thumb, forefinger and third finger of the right hand (her dominant hand) of several months duration [Figure 1a and b]. Her lesions used to subside with the application of topical corticosteroids, but would reappear on stopping them. Detailed questioning revealed that she was in the habit of plucking certa...

[Allergic contact dermatitis to cosmetics].

INTRODUCTION Contact dermatitis to cosmetics is a common problem in the general population, although its prevalence appears to be underestimated. We reviewed cases of allergic contact dermatitis to cosmetics diagnosed in our dermatology department over a 7-year period with a view to identifying the allergens responsible, the frequency of occurrence of these allergens, and the cosmetic products ...

[Allergic contact dermatitis to footwear in children].

Allergic Contact Dermatitis Physiology

Allergic Contact Dermatitis (ACD) involves the penetration of an allergen through the skin surface where it acts as a hapten by binding to epidermal proteins and eliciting, a delayed Type IV hypersensitivity reaction 48 to 120 hours after exposure. This immunologic response involves the activation of Th1 cells with the subsequent release of cytokines resulting in the classic inflammatory reaction.

Allergic contact dermatitis

Allergic contact dermatitis is a T cell mediated, antigen-specific inflammatory reaction of the skin due to repeated epicutaneous exposure to antigens. Immunologically it is divided into 2 phases, induction and elicitation phase. During the first phase which is clinically silent, naïve T cells are activated and differentiate into antigen-specific memory T cells. During the elicitation phase, af...